Necdin is a breast cancer metastasis suppressor that regulates the transcription of c-Myc

Metastasis is the primary cause of death in breast cancer. Earlier studies using a mammary tumorigenesis mouse model identified Necdin (Ndn) as a germline modifier of metastasis. Differential expression of Ndn induces a gene-expression signature that predicts prognosis in human breast cancer. Additi...

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Pubblicato in:Oncotarget
Autori principali: Lee, Minnkyong, Beggs, Sarah M., Gildea, Derek, Bupp, Sujata, Lichtenberg, Jens, Trivedi, Niraj S., Hu, Ying, Bodine, David M., Crawford, Nigel P.S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741624/
https://ncbi.nlm.nih.gov/pubmed/26384308
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