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Interferon-regulatory factor-1 (IRF1) regulates bevacizumab induced autophagy

PURPOSE: Antiangiogenic therapy is commonly being used for the treatment of glioblastoma. However, the benefits of angiogenesis inhibitors are typically transient and resistance often develops. Determining the mechanism of treatment failure of the VEGF monoclonal antibody bevacizumab for malignant g...

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Pubblicato in:Oncotarget
Autori principali: Liang, Ji, Piao, Yuji, Henry, Verlene, Tiao, Ningyi, de Groot, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741619/
https://ncbi.nlm.nih.gov/pubmed/26362401
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