Constitutive activation of MET signaling impairs myogenic differentiation of rhabdomyosarcoma and promotes its development and progression

Rhabdomyosarcoma (RMS) is a soft tissue sarcoma, which may originate from impaired differentiation of mesenchymal stem cells (MSC). Expression of MET receptor is elevated in alveolar RMS subtype (ARMS) which is associated with worse prognosis, compared to embryonal RMS (ERMS). Forced differentiation...

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Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Skrzypek, Klaudia, Kusienicka, Anna, Szewczyk, Barbara, Adamus, Tomasz, Lukasiewicz, Ewa, Miekus, Katarzyna, Majka, Marcin
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2015
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741613/
https://ncbi.nlm.nih.gov/pubmed/26384300
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