Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status

Mutational inactivation of the VHL tumor suppressor plays key roles in the development of renal cell carcinoma (RCC), and mutated VHL-mediated VEGF induction has become the main target for the current RCC therapy. Here we identified a signal pathway of VEGF induction by androgen receptor (AR)/miRNA-...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yuan, Sun, Yin, Rao, Qun, Xu, Hua, Li, Lei, Chang, Chawnshang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741598/
https://ncbi.nlm.nih.gov/pubmed/26304926
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