Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer

Diabetes mellitus and pancreatic cancer are intimately related, as approximately 85% of pancreatic cancer patients suffer from glucose intolerance or even diabetes. In this study, we evaluate the underlying mechanism by which hyperglycemia modulates the invasive potential of cancer cells and contrib...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Wei, Ma, Zhenhua, Ma, Jiguang, Li, Xuqi, Xu, Qinhong, Duan, Wanxing, Chen, Xin, Lv, Yunfu, Zhou, Shuang, Wu, Erxi, Ma, Qingyong, Huo, Xiongwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741592/
https://ncbi.nlm.nih.gov/pubmed/26439801
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