Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting

Differentiation has been proposed as a therapeutic strategy for glioblastoma (GBM) in part due to observations of stem-like cells in GBM that have been shown to undergo terminal differentiation in response to growth factor withdrawal and BMP activation. However, the effects of long term exposure to...

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Publicado en:Oncotarget
Autores principales: Balasubramaniyan, Veerakumar, Vaillant, Brian, Wang, Shuzhen, Gumin, Joy, Butalid, M. Elena, Sai, Ke, Mukheef, Farah, Kim, Se Hoon, Boddeke, H.W.G.M., Lang, Frederick, Aldape, Kenneth, Sulman, Erik P., Bhat, Krishna P., Colman, Howard
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741584/
https://ncbi.nlm.nih.gov/pubmed/26307681
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