Low EGFR/MET ratio is associated with resistance to EGFR inhibitors in non-small cell lung cancer

PURPOSE: Although activating mutations in the epidermal growth factor receptor (EGFR) gene are predictive markers for response to EGFR inhibitors, 30–40% of EGFR-mutant non-small cell lung cancer (NSCLC) patients are de novo non-responders. Hence, we sought to explore additional biomarkers of respon...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Silvia, Langley, Emma, Sun, Jong-Mu, Lockton, Steve, Ahn, Jin Seok, Jain, Anjali, Park, Keunchil, Singh, Sharat, Kim, Phillip, Ahn, Myung-Ju
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741578/
https://ncbi.nlm.nih.gov/pubmed/26439803
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