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Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples

As the development of resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has become an issue of concern, identification of the mechanisms responsible has become an urgent priority. However, for research purposes, it is not easy to obtain tumor samples from patien...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Ishii, Hidenobu, Azuma, Koichi, Sakai, Kazuko, Kawahara, Akihiko, Yamada, Kazuhiko, Tokito, Takaaki, Okamoto, Isamu, Nishio, Kazuto, Hoshino, Tomoaki
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741572/
https://ncbi.nlm.nih.gov/pubmed/26334838
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