PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway

The Hippo pathway significantly correlates with organ size control and tumorigenesis. The activity of YAP/TAZ, a transducer of the Hippo pathway, is required to sustain self-renewal and tumor-initiation capacities in cancer stem cells (CSCs). But, upstream signals that control the mammalian Hippo pa...

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Vydáno v:Oncotarget
Hlavní autoři: Fujimoto, Daisuke, Ueda, Yuki, Hirono, Yasuo, Goi, Takanori, Yamaguchi, Akio
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741490/
https://ncbi.nlm.nih.gov/pubmed/26431277
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