The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells

The function of imprinted H19 long non-coding RNA is still controversial. It is highly expressed in early embryogenesis and decreases after birth and re-expressed in cancer. To study the role of H19 in oncogenesis and pluripotency, we down-regulated H19 expression in vitro and in vivo in pluripotent...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zeira, Evelyne, Abramovitch, Rinat, Meir, Karen, Ram, Sharona Even, Gil, Yaniv, Bulvik, Baruch, Bromberg, Zohar, Levkovitch, Or, Nahmansson, Nathalie, Adar, Revital, Reubinoff, Benjamin, Galun, Eithan, Gropp, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741483/
https://ncbi.nlm.nih.gov/pubmed/26415227
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