LGR5 is associated with tumor aggressiveness in papillary thyroid cancer

PURPOSE: Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a cancer stem cell marker and a down-stream target in Wnt/β-catenin signaling. In human papillary thyroid cancer (PTC), over activation of Wnt/β-catenin has been associated with tumor aggressiveness. PATIENTS AND METHODS:...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Michelotti, Gregory, Jiang, Xiaoyin, Sosa, Julie Ann, Diehl, Anna Mae, Henderson, Brittany Bohinc
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741472/
https://ncbi.nlm.nih.gov/pubmed/26416247
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