Učitavanje...
Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination
LNX (Ligand of Numb Protein-X) proteins, LNX1 and LNX2, are RING- and PDZ-based E3-ubiquitin ligases known to interact with Numb. Silencing of LNX2 has been reported to down-regulate WNT and NOTCH, two key signaling pathways in tumorigenesis. Here we report the identification of the domain boundary...
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| Izdano u: | Oncotarget |
|---|---|
| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Impact Journals LLC
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4741457/ https://ncbi.nlm.nih.gov/pubmed/26451611 |
| Oznake: |
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