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Effects of Venlafaxine & Methadone Alone and in Combination with Spontaneous Morphine withdrawal Syndrome & Pain Sensation in Rats

INTRODUCTION: Methadone has been used as a drug to detoxify opioid tolerance. Naloxane precipitated morphine withdrawal behaviours were attenuated by venlafaxine as an antidepressant. On the contrary, after detoxifying the opioids, spontaneous withdrawal syndrome may occur with pain sensitivity. The...

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Publicat a:Basic Clin Neurosci
Autors principals: Fadaei-Kenarsary, Meisam, Farbood, Yaghoob, Taghi Mansouri, Seyed Mohammad, Fathi Moghaddam, Hadi
Format: Artigo
Idioma:Inglês
Publicat: Iranian Neuroscience Society 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741273/
https://ncbi.nlm.nih.gov/pubmed/27504153
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