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Histone H4 acetylation and the epigenetic reader Brd4 are critical regulators of pluripotency in embryonic stem cells

BACKGROUND: Pluripotent cells can be differentiated into many different cell types in vitro. Successful differentiation is guided in large part by epigenetic reprogramming and regulation of critical gene expression patterns. Recent genome-wide studies have identified the distribution of different hi...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Gonzales-Cope, Michelle, Sidoli, Simone, Bhanu, Natarajan V., Won, Kyoung-Jae, Garcia, Benjamin A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740988/
https://ncbi.nlm.nih.gov/pubmed/26847871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2414-y
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