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Biosynthetic route towards saxitoxin and shunt pathway

Saxitoxin, the most potent voltage-gated sodium channel blocker, is one of the paralytic shellfish toxins (PSTs) produced by cyanobacteria and dinoflagellates. Recently, putative biosynthetic genes of PSTs were reported in these microorganisms. We previously synthesized genetically predicted biosynt...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740887/
https://ncbi.nlm.nih.gov/pubmed/26842222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20340
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