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Biosynthetic route towards saxitoxin and shunt pathway

Saxitoxin, the most potent voltage-gated sodium channel blocker, is one of the paralytic shellfish toxins (PSTs) produced by cyanobacteria and dinoflagellates. Recently, putative biosynthetic genes of PSTs were reported in these microorganisms. We previously synthesized genetically predicted biosynt...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740887/
https://ncbi.nlm.nih.gov/pubmed/26842222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20340
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