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Biosynthetic route towards saxitoxin and shunt pathway

Saxitoxin, the most potent voltage-gated sodium channel blocker, is one of the paralytic shellfish toxins (PSTs) produced by cyanobacteria and dinoflagellates. Recently, putative biosynthetic genes of PSTs were reported in these microorganisms. We previously synthesized genetically predicted biosynt...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740887/
https://ncbi.nlm.nih.gov/pubmed/26842222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20340
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