Biosynthetic route towards saxitoxin and shunt pathway

Saxitoxin, the most potent voltage-gated sodium channel blocker, is one of the paralytic shellfish toxins (PSTs) produced by cyanobacteria and dinoflagellates. Recently, putative biosynthetic genes of PSTs were reported in these microorganisms. We previously synthesized genetically predicted biosynt...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Tsuchiya, Shigeki, Cho, Yuko, Konoki, Keiichi, Nagasawa, Kazuo, Oshima, Yasukatsu, Yotsu-Yamashita, Mari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740887/
https://ncbi.nlm.nih.gov/pubmed/26842222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20340
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