Gerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases

Gerstmann-Sträussler-Scheinker disease (GSS) is an inherited neurodegenerative disorder associated with mutations in the prion protein gene and accumulation of misfolded PrP with protease-resistant fragments (PrP(res)) of 6–8 kDa. With the exception of a few GSS cases characterized by co-accumulatio...

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Udgivet i:Sci Rep
Main Authors: Pirisinu, Laura, Di Bari, Michele A., D’Agostino, Claudia, Marcon, Stefano, Riccardi, Geraldina, Poleggi, Anna, Cohen, Mark L., Appleby, Brian S., Gambetti, Pierluigi, Ghetti, Bernardino, Agrimi, Umberto, Nonno, Romolo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740801/
https://ncbi.nlm.nih.gov/pubmed/26841849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20443
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