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Depletion of the LINC complex disrupts cytoskeleton dynamics and meiotic resumption in mouse oocytes

The SUN (Sad-1/UNC-84) and KASH (Klarsicht/ANC-1/Syne/homology) proteins constitute the linker of nucleoskeleton and cytoskeleton (LINC) complex on the nuclear envelope. To date, the SUN1/KASH5 complex is known to function as meiotic-specific factors. In this study, gene-silencing methods were used...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Luo, Yibo, Lee, In-Won, Jo, Yu-Jin, Namgoong, Suk, Kim, Nam-Hyung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740751/
https://ncbi.nlm.nih.gov/pubmed/26842404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20408
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