Risperidone-induced weight gain is mediated through shifts in the gut microbiome and suppression of energy expenditure

Risperidone is a second-generation antipsychotic that causes weight gain. We hypothesized that risperidone-induced shifts in the gut microbiome are mechanistically involved in its metabolic consequences. Wild-type female C57BL/6J mice treated with risperidone (80 μg/day) exhibited significant excess...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Bahr, Sarah M., Weidemann, Benjamin J., Castro, Ana N., Walsh, John W., deLeon, Orlando, Burnett, Colin M.L., Pearson, Nicole A., Murry, Daryl J., Grobe, Justin L., Kirby, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740326/
https://ncbi.nlm.nih.gov/pubmed/26870798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.10.018
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