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Cation Homeostasis in Red Cells From Patients With Sickle Cell Disease Heterologous for HbS and HbC (HbSC Genotype)

Sickle cell disease (SCD) in patients of HbSC genotype is considered similar, albeit milder, to that in homozygous HbSS individuals — but with little justification. In SCD, elevated red cell cation permeability is critical as increased solute loss causes dehydration and encourages sickling. Recently...

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Vydáno v:EBioMedicine
Hlavní autoři: Hannemann, A., Rees, D.C., Tewari, S., Gibson, J.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740305/
https://ncbi.nlm.nih.gov/pubmed/26870793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2015.09.026
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