Multimodal SHG-2PF Imaging of Microdomain Ca(2+)-Contraction Coupling in Live cardiac myocytes

RATIONALE: cardiac myocyte contraction is caused by Ca(2+) binding to troponin C, which triggers the cross-bridge power stroke and myofilament sliding in sarcomeres. Synchronized Ca(2+) release causes whole cell contraction and is readily observable with current microscopy techniques. However, it is...

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Gepubliceerd in:Circ Res
Hoofdauteurs: Awasthi, Samir, Izu, Leighton T., Mao, Ziliang, Jian, Zhong, Landas, Trevor, Lerner, Aaron, Shimkunas, Rafael, Woldeyesus, Rahwa, Bossuyt, Julie, Wood, Brittani, Chen, Yi-Je, Matthews, Dennis L., Lieu, Deborah K., Chiamvimonvat, Nipavan, Lam, Kit S., Chen-Izu, Ye, Chan, James W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740258/
https://ncbi.nlm.nih.gov/pubmed/26643875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307919
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