MIF is necessary for late-stage melanoma patient MDSC immune suppression and differentiation

Highly aggressive cancers “entrain” innate and adaptive immune cells to suppress anti-tumor lymphocyte responses. Circulating myeloid-derived suppressor cells (MDSCs) constitute the bulk of monocytic immunosuppressive activity in late stage melanoma patients. Previous studies revealed that monocyte-...

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Pubblicato in:Cancer Immunol Res
Autori principali: Yaddanapudi, Kavitha, Rendon, Beatriz E., Lamont, Gwyneth, Kim, Eun Jung, Al Rayyan, Numan, Richie, Jamaal, Albeituni, Sabrin, Waigel, Sabine, Wise, Ashley, Mitchell, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740231/
https://ncbi.nlm.nih.gov/pubmed/26603621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0070-T
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