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The D-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression?

Approximately 12% of histone H2B in mammalian brain contains an unusual D-aspartate residue in its N-terminal tail. Most of this D-aspartate is linked to the C-flanking glycine via an isopeptide bond. To explore the possible significance of these modifications, we generated an antibody the D-isoaspa...

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Vydáno v:Amino Acids
Hlavní autoři: Qin, Zhenxia, Zhu, Jeff X., Aswad, Dana W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740207/
https://ncbi.nlm.nih.gov/pubmed/26666674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-015-2140-9
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