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Uncoupling Caveolae from Intracellular Signaling In Vivo

RATIONALE: Caveolin-1 negatively regulates eNOS derived NO production and this has been mapped to several residues on Cav-1 including F92. Herein, we reasoned that endothelial expression of an F92ACav-1 transgene would let us decipher the mechanisms and relationships between caveolae structure and i...

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Détails bibliographiques
Publié dans:Circ Res
Auteurs principaux: Kraehling, Jan R., Hao, Zhengrong, Lee, Monica Y., Vinyard, David J., Velazquez, Heino, Liu, X., Stan, Radu V., Brudvig, Gary W., Sessa, William C.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4740205/
https://ncbi.nlm.nih.gov/pubmed/26602865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307767
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