Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization.

Class II molecules of the major histocompatibility complex (MHC) bind peptides derived from protein antigens delivered into endocytic compartments and present these peptides to CD4+ T cells. The precursors to functional MHC class II molecules loaded with peptides are complexes of the invariant chain...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Roche, P A, Teletski, C L, Stang, E, Bakke, O, Long, E O
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC47401/
https://ncbi.nlm.nih.gov/pubmed/8397411
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