Biofilm-associated bacterial amyloids dampen inflammation in the gut: oral treatment with curli fibres reduces the severity of hapten-induced colitis in mice

BACKGROUND/OBJECTIVES: A disruption of epithelial barrier function can lead to intestinal inflammation. Toll-like receptor (TLR) 2 activation by microbial products promotes intestinal epithelial integrity and overall gut health. Several bacterial species, including enteric bacteria, actively produce...

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Detalhes bibliográficos
Publicado no:NPJ Biofilms Microbiomes
Main Authors: Oppong, Gertrude O, Rapsinski, Glenn J, Tursi, Sarah A, Biesecker, Steven G, Klein-Szanto, Andres J P, Goulian, Mark, McCauley, Christine, Healy, Catherine, Wilson, R Paul, Tükel, Cagla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739805/
https://ncbi.nlm.nih.gov/pubmed/26855788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjbiofilms.2015.19
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