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Exploitation of a “hockey-puck” phenotype to identify pilus and biofilm regulators in Serratia marcescens through genetic analysis

Pili are essential adhesive determinants for many bacterial pathogens. A suppressor mutation screen that takes advantage of a pilus-mediated self-aggregative “hockey-puck” colony phenotype was designed to identify novel regulators of type I pili in Serratia marcescens. Mutations that decreased pilus...

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Publicado en:Can J Microbiol
Autores principales: Shanks, Robert M.Q., Stella, Nicholas A., Brothers, Kimberly M., Polaski, Denise M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739789/
https://ncbi.nlm.nih.gov/pubmed/26640000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/cjm-2015-0566
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