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Transmembrane chemokines act as receptors in a novel mechanism termed inverse signaling
The transmembrane chemokines CX3CL1/fractalkine and CXCL16 are widely expressed in different types of tumors, often without an appropriate expression of their classical receptors. We observed that receptor-negative cancer cells could be stimulated by the soluble chemokines. Searching for alternative...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739769/ https://ncbi.nlm.nih.gov/pubmed/26796342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10820 |
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