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Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

AMPylation of mammalian small GTPases by bacterial virulence factors can be a key step in bacterial infection of host cells, and constitutes a potential drug target. This posttranslational modification also exists in eukaryotes, and AMP transferase activity was recently assigned to HYPE Filamentatio...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Broncel, Malgorzata, Serwa, Remigiusz A., Bunney, Tom D., Katan, Matilda, Tate, Edward W.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739684/
https://ncbi.nlm.nih.gov/pubmed/26604261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.054429
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