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Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays

Protein tyrosine kinases (PTKs) play key roles in cellular signal transduction, cell cycle regulation, cell division, and cell differentiation. Dysregulation of PTK-activated pathways, often by receptor overexpression, gene amplification, or genetic mutation, is a causal factor underlying numerous c...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Kim, Hye-Jung, Lin, De, Lee, Hyoung-Joo, Li, Ming, Liebler, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739681/
https://ncbi.nlm.nih.gov/pubmed/26631510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O115.056713
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