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Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function

BACKGROUND: Helicobacter pylori MutS2 (HpMutS2), an inhibitor of recombination during transformation is a non-specific nuclease with two catalytic sites, both of which are essential for its anti-recombinase activity. Although HpMutS2 belongs to a highly conserved family of ABC transporter ATPases, t...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Damke, Prashant P., Dhanaraju, Rajkumar, Marsin, Stéphanie, Radicella, J. Pablo, Rao, Desirazu N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739419/
https://ncbi.nlm.nih.gov/pubmed/26843368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0629-3
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