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Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

By using a strategy based on nucleotide sequence homology, we have cloned a cDNA encoding a functional serotonin (5-HT) receptor. The deduced amino acid sequence of the 5-HT7 receptor displays limited homology with that of other 5-HT receptors. In addition to the seven stretches of hydrophobic amino...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ruat, M, Traiffort, E, Leurs, R, Tardivel-Lacombe, J, Diaz, J, Arrang, J M, Schwartz, J C
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8397408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.18.8547
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