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In Vitro Determination of Respimat(®) Dose Delivery in Children: An Evaluation Based on Inhalation Flow Profiles and Mouth–Throat Models

Background: Aerosol therapy in young children can be difficult. A realistic model based on handling studies and in vitro investigations can complement clinical deposition studies and be used to enable dose-to-the-lung (DTL) predictions. Methods: Predictions on dose delivery to the lung were based on...

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Podrobná bibliografie
Vydáno v:J Aerosol Med Pulm Drug Deliv
Hlavní autoři: Bickmann, Deborah, Kamin, Wolfgang, Sharma, Ashish, Wachtel, Herbert, Moroni-Zentgraf, Petra, Zielen, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739345/
https://ncbi.nlm.nih.gov/pubmed/26098994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2014.1166
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