ADAMTS-18 in the host tissues exerts little effect on breast tumor progress in a murine 4T1 breast cancer model

BACKGROUND: In this study, we aimed to identify a novel extracellular proteinase ADAMTS-18 that could be a potential tumor suppressor gene. RESULTS: We successfully constructed Adamts-18 knockout mice with BALB / c background. RT-PCR analysis showed syngeneic mammary tumor cell line 4 T1 per se has...

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Vydáno v:J Negat Results Biomed
Hlavní autoři: Liu, Min, Lu, Tiantian, Jing, Fang, Dang, Suying, Zhang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Brief Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4739331/
https://ncbi.nlm.nih.gov/pubmed/26841794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12952-016-0045-0
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