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Poorly soluble cobalt oxide particles trigger genotoxicity via multiple pathways
BACKGROUND: Poorly soluble cobalt (II, III) oxide particles (Co(3)O(4)P) are believed to induce in vitro cytotoxic effects via a Trojan-horse mechanism. Once internalized into lysosomal and acidic intracellular compartments, Co(3)O(4)P slowly release a low amount of cobalt ions (Co(2+)) that impair...
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| Publicado no: | Part Fibre Toxicol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4739324/ https://ncbi.nlm.nih.gov/pubmed/26843362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-016-0118-8 |
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