Cannabinoid CB2 Receptor Mediates Nicotine-Induced Anti-Inflammation in N9 Microglial Cells Exposed to β Amyloid via Protein Kinase C

Background. Reducing β amyloid- (Aβ-) induced microglial activation is considered to be effective in treating Alzheimer's disease (AD). Nicotine attenuates Aβ-induced microglial activation; the mechanism, however, is still elusive. Microglia could be activated into classic activated state (M1 s...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Jia, Ji, Peng, Jie, Li, Zhaoju, Wu, Youping, Wu, Qunlin, Tu, Weifeng, Wu, Mingchun
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738711/
https://ncbi.nlm.nih.gov/pubmed/26884647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4854378
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