Nkx3.1 controls the DNA repair response in the mouse prostate

BACKGROUND: The human prostate tumor suppressor NKX3.1 mediates the DNA repair response and interacts with the androgen receptor to assure faithful completion of transcription thereby protecting against TMPRSS2‐ERG gene fusion. To determine directly the effect of Nkx3.1 in vivo we studied the DNA re...

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Vydáno v:Prostate
Hlavní autoři: Zhang, Hailan, Zheng, Tian, Chua, Chee Wai, Shen, Michael, Gelmann, Edward P.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738428/
https://ncbi.nlm.nih.gov/pubmed/26660523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23131
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