Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth

The precise architecture of hair bundles, the arrays of mechanosensitive microvilli-like stereocilia crowning the auditory hair cells, is essential to hearing. Myosin IIIa, defective in the late-onset deafness form DFNB30, has been proposed to transport espin-1 to the tips of stereocilia, thereby pr...

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Veröffentlicht in:J Cell Biol
Hauptverfasser: Lelli, Andrea, Michel, Vincent, Boutet de Monvel, Jacques, Cortese, Matteo, Bosch-Grau, Montserrat, Aghaie, Asadollah, Perfettini, Isabelle, Dupont, Typhaine, Avan, Paul, El-Amraoui, Aziz, Petit, Christine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738386/
https://ncbi.nlm.nih.gov/pubmed/26754646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201509017
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