The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN

Bladder cancer causes an estimated 150,000 deaths per year worldwide. Although 15% of the recurrent bladder cancer becomes an invasive type, currently used targeted therapy for malignant bladder cancer is still not efficient. We focused on the miR-130 family (miR-130b, miR-301a, and miR-301b) that w...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Egawa, Hiroshi, Jingushi, Kentaro, Hirono, Takayuki, Ueda, Yuko, Kitae, Kaori, Nakata, Wataru, Fujita, Kazutoshi, Uemura, Motohide, Nonomura, Norio, Tsujikawa, Kazutake
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738343/
https://ncbi.nlm.nih.gov/pubmed/26837847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20574
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