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Persistence Increases in the Absence of the Alarmone Guanosine Tetraphosphate by Reducing Cell Growth

Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chowdhury, Nityananda, Kwan, Brian W., Wood, Thomas K.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738310/
https://ncbi.nlm.nih.gov/pubmed/26837570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20519
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