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Persistence Increases in the Absence of the Alarmone Guanosine Tetraphosphate by Reducing Cell Growth
Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738310/ https://ncbi.nlm.nih.gov/pubmed/26837570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20519 |
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