Active Tumor Permeation and Uptake of Surface Charge-Switchable Theranostic Nanoparticles for Imaging-Guided Photothermal/Chemo Combinatorial Therapy

To significantly promote tumor uptake and penetration of therapeutics, a nanovehicle system comprising poly(lactic-co-glycolic acid) (PLGA) as the hydrophobic cores coated with pH-responsive N-acetyl histidine modified D-α-tocopheryl polyethylene glycol succinate (NAcHis-TPGS) is developed in this w...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Hung, Chia-Chian, Huang, Wen-Chia, Lin, Yi-Wen, Yu, Ting-Wei, Chen, Hsin-Hung, Lin, Sung-Chyr, Chiang, Wen-Hsuan, Chiu, Hsin-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737719/
https://ncbi.nlm.nih.gov/pubmed/26909107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.13686
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