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The role of active-site aromatic and polar residues in catalysis and substrate discrimination by xylose isomerase.

The functions of individual amino acid residues in the active site of Thermoanaerobacterium thermosulfurigenes D-xylose ketol-isomerase (EC 5.3.1.5) were studied by site-directed substitution. The role of aromatic residues in the active-site pocket was not limited to the creation of a hydrophobic en...

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Autors principals: Meng, M, Bagdasarian, M, Zeikus, J G
Format: Artigo
Idioma:Inglês
Publicat: 1993
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC47376/
https://ncbi.nlm.nih.gov/pubmed/8378319
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