Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

Genome-wide association studies have successfully identified thousands of loci for a range of human complex traits and diseases. The proportion of phenotypic variance explained by significant associations is, however, limited. Given the same dense SNP panels, mixed model analyses capture a greater p...

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Publicat a:PLoS Genet
Autors principals: Xia, Charley, Amador, Carmen, Huffman, Jennifer, Trochet, Holly, Campbell, Archie, Porteous, David, Hastie, Nicholas D., Hayward, Caroline, Vitart, Veronique, Navarro, Pau, Haley, Chris S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737500/
https://ncbi.nlm.nih.gov/pubmed/26836320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005804
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