Microvesicles from Mesenchymal Stromal Cells Are Involved in HPC-Microenvironment Crosstalk in Myelodysplastic Patients

Exosomes/microvesicles (MVs) provide a mechanism of intercellular communication. Our hypothesis was that mesenchymal stromal cells (MSC) from myelodysplastic syndrome (MDS) patients could modify CD34(+) cells properties by MVs. They were isolated from MSC from MDS patients and healthy donors (HD). M...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Muntión, Sandra, Ramos, Teresa L., Diez-Campelo, María, Rosón, Beatriz, Sánchez-Abarca, Luis Ignacio, Misiewicz-Krzeminska, Irena, Preciado, Silvia, Sarasquete, María-Eugenia, de las Rivas, Javier, González, Marcos, Sánchez-Guijo, Fermín, del Cañizo, María-Consuelo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737489/
https://ncbi.nlm.nih.gov/pubmed/26836120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146722
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