Modulating the Substrate Stiffness to Manipulate Differentiation of Resident Liver Stem Cells and to Improve the Differentiation State of Hepatocytes

In many cell types, several cellular processes, such as differentiation of stem/precursor cells, maintenance of differentiated phenotype, motility, adhesion, growth, and survival, strictly depend on the stiffness of extracellular matrix that, in vivo, characterizes their correspondent organ and tiss...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Cozzolino, Angela Maria, Noce, Valeria, Battistelli, Cecilia, Marchetti, Alessandra, Grassi, Germana, Cicchini, Carla, Tripodi, Marco, Amicone, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737459/
https://ncbi.nlm.nih.gov/pubmed/27057172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5481493
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