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Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain

Trisomy of human chromosome 21 in Down syndrome (DS) leads to several phenotypes, such as mild-to-severe intellectual disability, hypotonia, and craniofacial dysmorphisms. These are fundamental hallmarks of the disorder that affect the quality of life of most individuals with DS. Proper brain develo...

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Bibliografische gegevens
Gepubliceerd in:Neural Plast
Hoofdauteurs: Lee, Han-Chung, Tan, Kai-Leng, Cheah, Pike-See, Ling, King-Hwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737457/
https://ncbi.nlm.nih.gov/pubmed/26881131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7434191
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