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DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection

Chronic hepatitis C virus (HCV) infection may progress to cirrhosis and hepatocellular carcinoma (HCC). Recently, two genetic variants, DEPDC5 rs1012068 and MICA rs2596542, were associated with the onset of HCC in Asian subjects with chronic HCV infection. The aim of the present study was to analyze...

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Veröffentlicht in:Hepatology
Hauptverfasser: Burza, Maria Antonella, Motta, Benedetta Maria, Mancina, Rosellina Margherita, Pingitore, Piero, Pirazzi, Carlo, Lepore, Saverio Massimo, Spagnuolo, Rocco, Doldo, Patrizia, Russo, Cristina, Lazzaro, Veronica, Fischer, Janett, Berg, Thomas, Aghemo, Alessio, Cheroni, Cristina, De Francesco, Raffaele, Fargion, Silvia, Colombo, Massimo, Datz, Christian, Stickel, Felix, Valenti, Luca, Romeo, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737289/
https://ncbi.nlm.nih.gov/pubmed/26517016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28322
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