Synthesis and Anti-Inflammatory Activity of Some O-Propargylated-N-acetylpyrazole Derived from 1,3-Diarylpropenones

In search of novel effective potent therapeutic agents delivered by oral route for inflammation treatment, some novel O-propargylated-N-acetylpyrazole analogs (5a–j) were prepared by treating N-acetylpyrazole (4a–j) derived from 1,3-diarylpropenones (3a–j) with propargyl bromide. Claisen-Schmidt con...

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Vydáno v:Int J Med Chem
Hlavní autoři: Dhingra, Ashwani Kumar, Chopra, Bhawna, Dass, Rameshwar, Mittal, Sanjeev K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737024/
https://ncbi.nlm.nih.gov/pubmed/26881075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/3156593
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